Researching into Asthma and Rhinitis
Hi! My name is Junaid and I am a medical student at the University of Manchester. I have taken a year out of my medical studies to spend some time doing a research masters in Medical Sciences. This means that I will be spending six years at university instead of the five normally required for medical school. I am currently conducting research into the treatment of asthma and rhinitis. I am hoping that this research will lead to permanent improvements in how we treat people with asthma. The reason I wanted to conduct research in this area is that I would like to become an Ear, Nose and Throat (ENT) surgeon in the future. One of the challenges of an ENT surgeon is managing patients who suffer from rhinitis and the effects it has on their asthma. Alongside this, I wanted gain an understanding about how research is conducted in hospitals. Since the way which doctors care for patients is evolving so quickly, research is an enormous aspect of our careers.
Rhinitis is a very common problem that affects a large number of people who suffer from asthma. It is described as the inflammation of the nose and can lead to symptoms such as a runny nose, sneezing and irritated eyes. These problems can affect people all year round and if you suffer from asthma you are more at risk of suffering from allergic rhinitis. This is a type of rhinitis that can be caused by allergies. From research in the past, it has been found that people who suffer from both allergic rhinitis and asthma at the same time experience a very poor quality of life. For this reason, I am investigating patients who attend asthma clinic for allergic rhinitis symptoms. This will help us understand the link between asthma and allergic rhinitis and how much of an impact both diseases make on people. Omalizumab is a medication that improves asthma symptoms which leads to people have a better quality of life. We do not know how this treatment affects people who suffer from both allergic rhinitis and asthma. By using questionnaires to find out how many people suffer from asthma and rhinitis and how well Omalizumab treats patients, we will be able to fine tune the treatments we give to people to make sure we are giving the right drugs to help them improve their asthma and allergic rhinitis symptoms.
To provide some further background on the conditions that I am studying you can visit the NHS choices websites for asthma and rhinitis.
Allergic Rhinits : http://www.nhs.uk/conditions/rhinitis---allergic/Pages/Introduction.aspx
World Allergy has provided a good overview about why asthma and rhinitis are linked and how they can affect people: http://www.worldallergy.org/public/allergic_diseases_center/caras/
Inflammation (swelling and redness) of the airways which connect the nasal passage and the mouth to the lungs is an important mechanism which causes people to suffer from asthma and rhinitis. The asthma centre provides a good overview on “What is Inflammation?” http://www.asthma.partners.org/NewFiles/Inflammation.html
The American Food and Drug Administration (FDA) has provided an information leaflet on Omalizumab and the main facts about how it works and the evidence behind its use: http://www.accessdata.fda.gov/drugsatfda_docs/label/2003/omalgen062003LB.pdf